Leadership
Leonardo Sileo
CEO & Founder
Marco Pisanello
CTOFounders
John A. Assad
FounderProfessor of Neurobiology and Director of the Harvard Program in Neuroscience, Harvard Medical School
Sandeep Robert Datta
FounderProfessor of Neurobiology, Harvard Medical School
Massimo De Vittorio
Founder Principal Investigator, Center for Biomolecular Nanotechnologies, Istituto Italiano di Tecnologia
Full Professor, Technical University of Denmark
Ferruccio Pisanello
FounderPrincipal Investigator and Center Coordinator, Center for Biomolecular Nanotechnologies, Istituto Italiano di Tecnologia
Bernardo L. Sabatini
Founder Alice and Rodman W. Moorhead III Professor of Neurobiology, Harvard Medical School
Co-Director of the Kempner Institute for the Study of Natural and Artificial Intelligence, Harvard University
Mission
OptogeniX develops, manufactures, and commercializes innovative technologies for optical interfacing with the brain, combining versatility with minimized invasiveness. Our goal is to overcome the limitations of currently available tools and enable new possibilities in neuroscience research.
We work closely with researchers to continuously advance the Lambda Fibers technology and expand its capabilities through the integration of additional functionalities (e.g. electrical recording, biosensing, and drug delivery). Looking ahead, our ambition is to extend the technology to new research areas and, ultimately, to medical applications.
History
OptogeniX originated from a research collaboration launched in 2012 between neuroscientists at Harvard Medical School (HMS) and researchers at Istituto Italiano di Tecnologia (IIT). The collaboration aimed to develop a new generation of implantable probes for neurophysiology and optogenetics that could overcome the limitations of the tools available at the time.
The most significant outcome of this research was a technology based on tapered optical fibers, combined with an unconventional method for coupling light into them. This approach was soon recognized as a unique and highly effective solution for enabling more versatile and efficient optogenetic stimulation of neurons in vivo.
Founded in 2014, OptogeniX brings this technology to research laboraties around the world. Today, we provide Lambda Fibers and dedicated equipment to more than 200 labs.
Milestones
2014
OptogeniX is founded
2016
Growing adoption of Lambda Fibers worldwide
2017
Launch of OptogeniX equipment for spatial selective operation of Lambda Fibers
2018
First independent publication demonstrating the successfull use of Lambda Fibers
2019
Lambda Fibers are established as a tool for fiber photometry
2025
Lambda fibers are employed for in vivo Raman spectroscopy